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We had the privilege to comment on a potentially transformative strategy from Steven Pollard and colleagues at @EdinUni_IRR that hijacks a SOX2/SOX9 gene control to switch to turn on a suicide gene and immunotherapy in brain tumour cells. Read more in @Nature: rdcu.be/fcnpk #braincancer #stemcells
We are delighted to commemorate 10 years of outstanding achievements in biomedical research at the 2-day #SBMS 10th Anniversary Research Symposium on 11 and 12 Dec 2025. Thank you all for contributing to this memorable occasion. Here’s to continued innovation and collaboration!
The Master of Biomedical Innovation at #SBMS is designed to transform scientific discovery into tangible healthcare solutions. Join our online session on 23 Mar to learn how this programme prepares you to lead the next wave of biomedical advancement: hku.au1.qualtrics.com/jfe/form/SV_...
We had the pleasure of welcoming 49 eager secondary school students to our #HKU Biomedical Summer Academy 2025. Supported by Croucher Foundation, this engaging week-long programme allowed #SBMS researchers and experts to introduce them to the fascinating field of biomedical sciences.
Enjoy feature stories about the revamped BBiomedSc programme in the academic year 2025/26, as well as the Croucher Summer Course – Precision Genome Engineering; and check out the research highlight contributed by Dr. Yan Xue! online.flippingbook.com/view/7447824...
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In a new paper from the lab we show that engineered SOX17 and miniSOX not only replace but outperform SOX2 in driving derivation of induced expanded potential stem cells - a platform to model early development and discover new antiviral and anti‑ageing therapies. 🔗 www.nature.com/articles/s42...
It's been great of have @alexdemendoza.bsky.social visit and inspire us at @hkusbms.bsky.social. It looks like DNA methylation has even deeper roots in our ancestry than Sox 🤔. But it's been the evolution of the latter connecting us scientifically and we could finally meet up in person.
New cancer therapies are needed that do not harm healthy tissue. An engineered DNA sequence shows promise as one of the tools in a method to target brain tumour cells. New cancer therapies are needed that do not harm healthy tissue. An engineered DNA sequence shows promise as one of the tools in a method to target brain tumour cells.
rdcu.be
Tumour trap: engineered enhancer sequences enlisted to kill cancer cells | Nature
Less than a month left until our official QMUL Centre for Epigenetics Launch Conference! We will have an amazing list of guest speakers, including Ralf Jauch @ralfhku.bsky.social from The University of Hong Kong. Book your free ticket now! www.eventbrite.co.uk/e/qmul-centr... #qmul #epigenetics
#ISSCR2025 co-chaired by Prof Kathryn Cheah culminated in June with a panel session featuring members of the HK Spinal Muscular Atrophy community, highlighting the transformative power of patient advocacy, clinical expertise & gov't collaboration in improving treatment access.
We had an inspiring presentation when Ben Becker took us along to delve deep inside our brains and visualise how they process emotions, with implications for mental health. To all 50+ participants, thank you for coming! Host: @ralfhku.bsky.social #KEseminar #GermanConsulateGeneralHongKong
HKU SBMS Newsletter Issue 21
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Apr 25, 2025
May 8, 2025
Ralf Jauch
Jun 19, 2025
May 22, 2025
HKU School of Biomedical Sciences
Enhancing reprogramming towards induced human expanded pluripotency through substitution of SOX2 with engineered SOX17 transcription factors - Communications Biology
Engineered SOX17 factors, including a miniaturized variant, replace SOX2 to drive efficient direct reprogramming to induced human expanded potential stem cells under feeder-based and feeder-free cultu...
www.nature.com
HKU School of Biomedical Sciences
HKU School of Biomedical Sciences
HKU School of Biomedical Sciences
Ralf Jauch
Ralf Jauch
HKU School of Biomedical Sciences
HKU School of Biomedical Sciences
QMUL Centre for Epigenetics