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Thrilled to share a new preprint! 📝 🎉 Lewis lab PhD student Casadora wondered: Do mtDNA synthesis and lipid droplet biogenesis co-occur at the same membrane contact sites? Or can we discern distinct ER-mito contact classes? Evidence suggests the latter, relevant in overnutrition!
10mo
www.biorxiv.org/content/10.1...
10mo
www.biorxiv.org
Fatty acids are trafficked between organelles to support membrane biogenesis and act as signaling molecules to rewire cellular metabolism in response to starvation, overnutrition, and environmental cu...
Saturated lipid stress attenuates mitochondrial genome synthesis in human cells
Sam Lewis, Ph.D.
Sam Lewis, Ph.D.