Neuroscientist at Mount Sinai NYC, Simons Collaboration on Plasticity and the Aging Brain Fellow
work: PhaSER, inhibition, oscillations, epilepsy, and aging
play: sewing, knitting, and sunshine
www.zoechristensonwickphd.com
Zoé Christenson Wick
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🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
Interested in studying how neural circuits underlying mental health disorders are shaped by experience (e.g., stress)? Also interested in being trained by an amazing, thoughtful, and rigorous scientist? Also interested in living in a beautiful Canadian city? See below!
Zoé Christenson Wick
Abhilasha Joshi, PhD
We're brewing up some Halloween fun in the Cai & Shuman Labs! ⚗️🎃
Just look at all the creativity everyone poured into their costumes! We have the coolest crew 👩🔬🧪
Reunion with past and present Cai lab & Shuman lab members (and collaborators). Spending time with you guys is easily the best part of my job.
@tristanshuman.bsky.social
@sinaibrain.bsky.social
@sfn.org
🧠 The Cai Lab will be at #SfN25!
Be sure to stop by the poster sessions to check out Hailey's work on decision-making, @zachtpennington.bsky.social's work on stress, @zoechristensonwick.bsky.social's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
Check out new work from our lab! We developed a new way to directly control the precise timing of interneurons during behavior and found that theta phase locking is a causal mediator of seizure susceptibility in both healthy and epileptic mice.
Amazing! Congratulation Zoe 💪🥳this great application of #BiPOLES and a really cool paper👍
Denise J. Cai, Ph.D.
Denise J. Cai, Ph.D.
Denise J. Cai, Ph.D.
In #SanDiego for @sfn.org's #SfN2025? The #ShumanLab's Paul Philipsberg & @zoechristensonwick.bsky.social are! CATCH UP with them & LEARN ABOUT their EXCITING WORK! #FriedmanBrainInstitute #NashNeuroscience #FBIatSfN CHECK OUT the #FBIatSfN Itinerary ➡️ files.constantcontact.com/d41ee115401/...
We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠
Johannes Vierock
Tristan Shuman
🚨New preprint alert🚨
We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)
The Friedman Brain Institute
The Friedman Brain Institute
Zoé Christenson Wick
Video
I’m hiring at all levels and accepting graduate students through Psychology and the Graduate Program in Neuroscience. Reach out if you’re interested in joining a collaborative, fun, creative, and supportive team in beautiful Vancouver! 🏔️ ⛷️ 🏖️ 🌆
Zach Pennington
(This is the part of the paper where I had to summarize many. many. many. years of work in 2 sentences):
PhaSER works best to shift the phase locking of interneurons when coupled with bidirectional manipulations (thank you, BiPOLES!!!) 👏 @simwieg.bsky.social @johvierock.bsky.social