A gene is recurrently mutated in cancer. But do these mutations really cause the disease? Or are they merely selected during normal tissue evolution?
Postdoc D. Cheek had the creative idea to use patient ages to try and answer this question.
Read new paper out here:
www.nature.com/articles/s41...
Mutations may be enriched in tumor samples because they promote carcinogenesis or because they promote clonal expansions in healthy tissue. This study mathematically disentangles these two possibiliti...
