The first C. elegans paper from lab! We find that, similar to mammals, tRNA-fragments (or the new name in the field tDRs) accumulate in worm sperm and can transmit non-genetically inherited phenotypes to offspring. We also find an RNase that regulates their processing, showing that length matters
Colin Conine
tRNA-derived RNA processing in sperm transmits non-genetically inherited phenotypes to offspring in C. elegans https://www.biorxiv.org/content/10.1101/2025.04.14.648817v1
