Prof. Univ. of Bergen & Helse Bergen | Basic & translational science | Molecular Biology | Cancer | Endocrinology | Rare diseases | Cytoskeleton | Ribosome | Protein biogenesis | PTMs | N-terminal acetylation
https://www.uib.no/en/rg/protein
Thomas Arnesen
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Structure of the E3 ligase CRL2ZYG11B with substrates reveals the molecular basis for N-degron recognition and ubiquitination. @ispt-proteinterm.bsky.social @cp-cellreports.bsky.social www.cell.com/cell-reports...
Liu et al. define how the CRL2ZYG11B ubiquitin ligase assembles and recognizes Gly/N-degron
substrates by cryo-EM. Structures with an NLRP1 Gly/N-degron and SARS-CoV-2 ORF10
reveal extended substrate-...
#Proteintermini2026 is about to begin! This beautiful room in the heart of Palermo will be our home for the next four days 🤩
1/ Sharing my article in TIBS:
"Science is always unfinished: rethinking the demand for complete stories."
The cost of that demand: delayed dissemination, cherry-picked data, and an endless "one more experiment" loop.
authors.elsevier.com/a/1n0XU3S6Gf...
As predicted, the food at #Proteintermini2026 is delicioso! Trying hard to resist these ricotta-filled pastries with candied orange
📽️ G&D Tapes 📽️
G&D Author, Lucas Unger, tells us about an auto-regulatory loop between HNF1A and Hedgehog signaling that dictates stem cell lineage specification.
New in #genesdev:
➡️ https://genesdev.cshlp.org/content/40/11-12/805.full
Simona Chera & Cell Fate Lab Lucas Unger Luiza Ghila
And we’re off! @giglionelab.bsky.social introduces FEBS Workshop #Proteintermini2026 Looking forward to four days of great science
