Is neuroscience research really working to understand the human brain? Or do we get lost in mouse cognition? I’ve asked myself this a lot since starting to work with human tissue. Our first Jonas Lab foray into untangling human hippocampal circuits is now online! www.cell.com/cell/fulltex... 1/a few
Human hippocampal CA3 networks use sparse and broad synaptic connectivity, and their recurrent synapses employ reliability, precision, and long integration times to enhance memory capacity. Thus, the human hippocampus is distinct from both rodent counterparts and human neocortical circuits.