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Excited to see our work on IGHC diversity out! Huge shoutout to @uddalok.bsky.social for leading this study. šŸ§¬ The data is now available on VDJbase, our open resource for exploring B and T cell germline variation across populations. šŸ§‘ā€šŸ”¬ Go and Explore vdjbase.org! #immunogenetics #VDJbase
7mo
VDJbase
vdjbase.org
Happy to announce the publication of our work exploring under-appreciated genetic diversity in the human IGHC region. Awesome work by @uddalok.bsky.social. So grateful for our amazing co-authors. @williamlees.bsky.social @guryaari.bsky.social @ayeletperes.bsky.social www.cell.com/cell-genomic...
7mo
www.cell.com
Genetic variation within immunoglobulin heavy chain constant (IGHC) genes modulates interactions between antibodies and other immune receptors and effector cells, directing cell killing and the cleara...
The human IG heavy chain constant gene locus is enriched for large structural variants and coding polymorphisms that vary among human populations
Corey Watson