Radiotherapy against cancer can cause skin inflammation and scarring. This paper identifies a protein called DKK3 as a key regulator of radiation-induced epidermal hyperplasia and skin fibrosis — highlighting it as a promising therapeutic target.
www.nature.com/articles/s41...
Signal Transduction and Targeted Therapy - Wnt-associated DKK3 in keratinocytes mediates radiation-induced hyperplasia, dermatitis and skin fibrosis
