Thrilled to see our story led by graduate student, Linh Pham, out in print! Linh's work reveals how #NRF2 impedes innate-adaptive crosstalk during #TB infection by inhibiting alveolar #macrophage MHC II expression. www.cell.com/cell-reports...
Pham et al. show that, during Mycobacterium tuberculosis infection, NRF2 activation
in alveolar macrophages inhibits MHC II but not MHC I, leading to dampening of antigen
presentation and CD4+ T cell ...