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Thrilled to see our story led by graduate student, Linh Pham, out in print! Linh's work reveals how #NRF2 impedes innate-adaptive crosstalk during #TB infection by inhibiting alveolar #macrophage MHC II expression. www.cell.com/cell-reports...
Pham et al. show that, during Mycobacterium tuberculosis infection, NRF2 activation in alveolar macrophages inhibits MHC II but not MHC I, leading to dampening of antigen presentation and CD4+ T cell ...
NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection
www.cell.com
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Alissa Rothchild