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Postdoctoral Research Fellow Women‘s health | Neuroendocrinology | Neuroimaging (she/her)
Carina Heller, Ph.D.
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Thank you to an incredible team of co-authors and collaborators making this work possible 🙏
1mo
Carina Heller, Ph.D.
🧠 Adolescence is a critical window for both brain development and the emergence of mental health symptoms. Yet, much of the published work has focused on chronological age, overlooking a key biological and normative milestone: Menarch.
🚨This normative and easily identifiable marker could define a critical window for mental health screenings with greater precision than current age-based guidelines.
1mo
The onset of menarche, largely independent of age of menarch and socio-environmental factors, preceded a significant spike in internalizing symptoms, while altering the rate of ongoing structural brain development.
These findings suggest that menarche is not only a reproductive milestone but also a *neuroendocrine driver of adolescent brain and mental health trajectories*. Yet, menarche remains an underutilized milestone, often documented but rarely integrated in clinical practice.
@hollysully.bsky.social @martingell.bsky.social @koiralasanju.bsky.social John McClellan France Ran Barzilay Tyler M Moore Ka I Ip @drdamienfair.bsky.social @tervoclemmensb.bsky.social @ariellekeller.bsky.social Adriene M. Beltz @emilyjacobs.bsky.social @bart-larsen.bsky.social
1mo
In this study, leveraging data from the ABCD study, we found that menarche onset marks a pivotal inflection point in trajectories of internalizing symptoms and gross brain morphormetry.
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🚨Preprint Alert 🧠 Our new preprint „Menarche onset is an inflection point for mental health and brain development“ is now online! 👉 Preprint available here: www.biorxiv.org/content/10.6...
Carina Heller, Ph.D.
1mo
Carina Heller, Ph.D.
Carina Heller, Ph.D.
Carina Heller, Ph.D.
🚨 New preprint alert! 🚨 Transdiagnostic latent factor models of psychopathology are widely assumed to improve brain-behaviour associations. So we decided to test this directly and found that they don't. A short 🧵 Link: www.biorxiv.org/content/10.6... 1/10
Carina Heller, Ph.D.
Carina Heller, Ph.D.
3mo