Updates from the Nancy Keller Lab at the University of Wisconsin-Madison
Fungal genetics, genomics, and secondary metabolism. 🍄 Managed by grad students
Website: https://sites.google.com/view/kellerlabuw/keller-lab-home?authuser=0
Keller Lab
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Remember: All mushrooms are edible, but some are edible only once! 🍄
Our lab's research made it into @hankgreen.bsky.social and @scishow.bsky.social 's latest video on the death cap! Watch it here: www.youtube.com/watch?v=PNL_...
New preprint day!! @laurafabre.bsky.social took 1k RNAseq samples and built an atlas of lncRNAs across four Aspergillus species, expanding the gene content of each by up to 20% and discovering a novel modulator of aflatoxin production. w/ @kellerlab.bsky.social.
Recently, Dr. Keller was featured on the podcast "The Life Lab by Death Clock," where she discussed molds and mycotoxins, and their impacts on the food supply chain.
Curious? Listen here:
Spotify (urldefense.com/v3/__https:/...)
Apple Podcasts (podcasts.apple.com/us/podcast/d...)
Identification of this fungal RiPP subclass, spearheaded by Dr. Sung Chul Park, was also highlighted by UW-Madison in a recent press release: ls.wisc.edu/news/the-cha...
☠️🍄The world's deadliest mushroom has been hiding a secondary metabolite secret! The Keller, Drott & Pringle Labs just published in @pnas.org: leaderless RiPPs, a peptide class never before seen in fungi, found in Amanita phalloides and linked to its Californian invasion. www.pnas.org/doi/10.1073/...
☠️🍄The world's deadliest mushroom has been hiding a secondary metabolite secret! The Keller, Drott & Pringle Labs just published in @pnas.org: leaderless RiPPs, a peptide class never before seen in fungi, found in Amanita phalloides and linked to its Californian invasion. www.pnas.org/doi/10.1073/...
doi.org
Amelia Barber
Podcast Episode · The Life Lab by Death Clock · May 29 · 42m
University of Wisconsin–Madison researchers just released a groundbreaking study on the same mushrooms behind an uptick in poisonings in California.
ls.wisc.edu
Meet Nancy Keller, one of our plenary speakers! Dr. Keller's research focuses on the discovery of secondary metabolite synthases and their chemical products and the intrinsic development of antifungal resistance in Aspergillus pathogens. Register today for #CFN25 to hear more from Dr. Keller.
Keller Lab
Keller Lab
Keller Lab
Especially happy to be finishing this project, it taught me so much. doi.org/10.64898/202...
Thanks for the journey, @ameliabarberphd.bsky.social and @kellerlab.bsky.social!
doi.org
Very happy to see this published: doi.org/10.1093/nar/...: a GRN-based approach to predict regulatory subnetworks for developmental and pathogenic processes in Aspergillus fumigatus and GRAsp: a network viz tool: grasp.wid.wisc.edu with @jeanmichelane.bsky.social and Nancy Keller labs!
Abstract. Aspergillus fumigatus is a notorious pathogenic fungus responsible for various harmful, sometimes lethal, diseases known as aspergilloses. Unders
