Fascinating new work reveals how anti-CV2/CRMP5 autoantibodies may be a potential driver of neuropathic pain in paraneoplastic syndromes. This mechanistic insight suggests a new therapeutic approach for patients. www.nature.com/articles/s41...
Lung and thymoma cancer patients often suffer from autoimmunity and related painful neuropathies. Here the authors show that patient-derived anti-CRMP5 autoantibody binds to rat dorsal root ganglia to...