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Paediatric nephrologist in Bristol, progressing kidney gene 🧬therapy, mum of boys, loves ballet/ gymnastics/ dance
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Kidney disease affects 1 in 10 of the UK population and has largely been overlooked in the UK 10 Year Health Plan. Please sign this petition by Thursday 9th October to emphasise the importance of a national strategy for kidney disease. www.ukkidney.org/prime-minist...
Great talk about the Hidden initiative from Kate Bramham and detecting CKD in the community in London. Absolutely inspirational @kidneyresearchuk.org
Interesting!
8mo
Having a fantastic time listening to all the progress in kidney research in the UK @kidneyresearchuk.org driving discoveries. Fantastic talk @willkidney.bsky.social about how large well designed trials have changed our practice in nephrology
8mo
Apr 2, 2025
8mo
Kidney disease affects more than 7 million people in the UK, yet was largely overlooked in the Government’s new 10-year health plan for the NHS. Without action, it will place an unsustainable burden o...
www.ukkidney.org
Add Your Name: Call on the Prime Minister to Tackle Kidney Disease
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It’s #WorldImmunizationWeek Vaccines have saved 154 million lives in the last 50 years. That’s 6 lives every minute. A reminder of what is #HumanlyPossible. Science saves lives. #VaccinesWork bit.ly/wiw2025
Other than the brain, our immune system is the most complex part of the human body. For the first time, sequencing receptors of B and T cells, along w/ generative A.I., enabled diagnosis of medical conditions such as lupus. That's just for starters. erictopol.substack.com/p/the-first-...
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Sibeprenlimab inches closer to approval www.hcplive.com/view/fda-acc... feat @brendonneuen.bsky.social Phase 3 RCT next week at #ERA25 (& some journal?)
Your kidneys are working hard for you every day, every hour. Return the favor with these small habits that lead to lifelong health. 💬 Which of these do you already do? Which one could you start this week? #KidneyFacts #HealthyKidneys #NephrologyTips #BIGKiDsStudy #KidneyHealthAwareness #sampsonlab
Apr 24, 2025
Feb 23, 2025
May 29, 2025
10mo
Sparsentan for FSGS?? It's alive.... ir.travere.com/press-releas...
With the priority review acceptance of the Biologics License Application, the FDA has assigned a PDUFA target action date of November 28, 2025.
www.hcplive.com
FDA Accepts, Grants Priority Review to Sibeprenlimab BLA for IgA Nephropathy
So excited to share our new paper out today in @nature.com. We repurposed R2 retrotransposons to create STITCHR, a tool that can make virtually any kind of edit in mammalian genomes including the scarless multi-kilobase scale insertions 🧵 www.nature.com/articles/s41...
WHO
Eric Topol
May 20, 2025
Apr 9, 2025
Travere Therapeutics Announces FDA Acceptance of sNDA for FILSPARI® (sparsentan) in FSGS
PDUFA target action date of January 13, 2026 If approved, FILSPARI would be the first and only FDA-approved treatment for FSGS, a rare kidney condition and a leading cause of kidney failure Travere Th...
ir.travere.com
A study of retrotransposon activity repurposes a retroelement called R2Tocc to create a programmable system called STITCHR that enables diverse genome edits including efficient, scarless large pa...
Reprogramming site-specific retrotransposon activity to new DNA sites - Nature
www.nature.com
Swapnil Hiremath 🍁🇨🇦
1️⃣ Now this is amazing! 🎉 My PhD student Gráinne Butler led a groundbreaking study using Epic EMR data to detect genetic kidney disease before symptoms appeared!
Sampson Lab for Kidney Genomics
Feb 17, 2025
Michelle Rheault, MD
Chris Fell
Cathy Quinlan ☘️ 🇦🇺 🌱