Calcium spikes know which way the wind blows!
Lily Nguyen and I wrote a dispatch on this fascinating work led by Itzel [email protected]+Gaby Maimon!
authors.elsevier.com/a/1mfk53QW8S...
Yvette Fisher
www.cell.com/cell/fulltex...
We had a lot of fun working on this project (led by Itzel Ishida, not on bluesky). Some interesting highlights from the paper -
In the fly central complex, PFNa neurons switch from firing classical sodium spikes
when depolarized to firing non-canonical T-type calcium spikes when hyperpolarized.
This bidirectional spiking allow...