PhD student | Mannervik lab | Stockholm University | developmental epigenetics and chromatin of Drosophila| histone acetylation and methylation
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Have you ever wondered how chromatin states shape developmental trajectories? In our preprint, we address this question using single-cell nanoCUT&Tag, a method developed by Marek Bartosovic @mardzix.bsky.social, which simultaneously profiles active H3K27ac and repressive H3K27me3 in the same nucleus
It was a fantastic exploration during my PhD, a new method, with new struggles. I had an amazing team of Artem and Aleksander to deal with all of them. Also my first experience of project supervision, it was hard but extremely cool. And thanks to @mardzix.bsky.social and Pepe for all the support!
www.biorxiv.org
If you know a graduating undergraduate looking for the chance to spend 1-2 years in a lab before graduate school, we're hiring! Our lab explores morphogenesis, defining how the cell adhesion & cytoskeletal machinery work together to allow cells to change shape & move tarheels.live/peiferlab/ 1/n RT
Sergei Pirogov
Mannervik Lab
Have you ever wondered how chromatin states shape developmental trajectories? In our preprint, we address this question using single-cell nanoCUT&Tag, a method developed by Marek Bartosovic @mardzix.bsky.social, which simultaneously profiles active H3K27ac and repressive H3K27me3 in the same nucleus
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Male octopuses use a specialized arm that acts as both a sensory and reproductive organ to navigate the female’s mantle, locate oviducts, and transfer sperm. These findings reveal how sensory systems shape reproductive behavior and drive speciation.
Learn more in Science: https://scim.ag/4dYMtFq
(1/14) Excited to share our new preprint: ArChIPelago — classic ML on top of multiple PWMs improves genomic TFBS prediction. shorturl.at/jnxDA
Builds on our MEX paper (Vorontsov et al., 2025).
w/ @pensarata.bsky.social
@vorontsovie.bsky.social
@sevamakeev.bsky.social
@halfacrocodile.bsky.social
www.biorxiv.org
Evdokimova, A. A., Kolesnikova, T. D., Mazina, M. Y., ...., Vorobyeva, N. E. (2025). Transcriptional induction by ecdysone in Drosophila salivary glands involves an increase in chromatin accessibility and acetylation. Nucleic Acids Res, 53(7) pmc.ncbi.nlm.nih.gov/articles/PMC...
