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Scientific Visualization (PhD) | Viroscope | Revealing the cinematic universe inside your cells | High-End Microscopy & Storytelling

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Check out the final part in the series of #InTheLabWithProteintech !

The art of the waiting game. Rodent deltavirus (RDeV) is a satellite virus. It doesn't kill, but moves in like a quiet tenant, replicating while waiting for a partner in crime, a helper virus, to provide its transport. 🟨 Actin 🟦 Delta Antigen ⬜ DNA 🔬: Imaged by me.

#FluorescenceFriday A Maximum Projection of three U2OS cells capturing two different steps of cell division. Sister cells are split but tethered by a midbody remnant. 💛 Actin: Spiky/explosive 💙 DNA: Varing conformations 🖤 Microtubules: Dark depth Separation takes time.

Building a cellular village 🔬🏘️ You've seen a Tasmanian Devil, but not like this! This super-res cluster of fibroblasts shows one cell building a new unit for the community. 💛 Actin 🩷 DNA 🩵 Tubulin The cyan mitotic spindle is ready for the heavy lifting! Fav mitosis stage? ⬇️

10h into active viral pathogenesis. Lung cells infected with VSV, showing vesicle trafficking under siege. 🩷 GFP: Replicating virus 💙 Rab11: Endosome network Clear cytopathic distress: extensive membrane blebbing & abnormal nuclear shapes. 🔬 @viroscope.bsky.social. 1 slice, 1 img/sec.

SARS-CoV-2 replicating inside primary Human Airway Epithelia 🟩 Actin: Highlight brush-like cilia and cell-cell junctions 🟪 dsRNA: Replicating virus This image made the cover of Journal of Virology for April 2021.

Septins: the oft forgotten 4th component of the cytoskeleton. This shot of the basal layer reveals SEPT7 (Gold) and SEPT8 (Cyan) in all their structural glory. Check out the blog post and the @proteintech.bsky.social antibody below! ⏬⏬

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#InTheLabWithProteintech! Go check out the blog post behind the image, and how @proteintech.bsky.social antibodies helped me in my work on viral restriction : bit.ly/4242DX8

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Inner Space: A Cellular Cosmos Two human fibroblasts mimicking cosmic solar bodies. 💛 Actin: Radiating star filaments 🩵 Tubulin: Plasma highways ❤️ DNA: Crimson core We are a universe ourselves. At Viroscope Imaging, we make data breathtaking. Let's elevate your R&D! 🔬 #FluorescenceFriday #SciArt

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Viroscope

Discover how Dr Joe McKellar uses Proteintech antibodies in confocal microscopy to study viral infections.

Scientist Stories: How Dr Joe McKellar uses Proteintech antibodies in Confocal Microscopy to Study Viral Infections

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Viroscope

The final image in our #InTheLabWithProteintech series with Dr Joe McKellar, a 4-colour map of the neuronal cytoskeleton, before the viruses were ever introduced. 🟡 Actin 🔵 Vimentin 🟢 Tubulin 🩷 DNA Read series: https://bit.ly/4e3ehqR Imaged with ZEISS LSM980 + Airyscan 2

Part two of #InTheLabWithProteintech with Dr Joe McKellar, with septins this time, the “fourth component” of the cytoskeleton, imaged at the basal layer of A549 cells. 🟡 Gold: SEPT7 🔵 Cyan: SEPT8 Read more: https://bit.ly/4d5OE9y @viroscope.bsky.social #InTheLabWithProteintech

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We're back with our #InTheLabWithProteintech series, with Dr Joe McKellar, a CiteAb Image of the Year winner. A549 cells, 24h into an influenza A infection. 🟡 Gold: YBX1 (hijacked by the virus to replicate) 🔵 Blue: viral nucleoprotein ⚫ Grey: DNA https://bit.ly/4242DX8

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Proteintech