The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
The Journal of Physiology
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'The #LINC complex in blood vessels: from physiology to pathological implications in #arterioles' 🫀 🔎
In this review, Gonzalo Ferreira and colleagues elucidate the LINC complex's role in health and disease 📜
physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Dysregulation of #neural tube vascular development as an aetiological factor in autism spectrum disorder: Insights from valproic acid exposure'🫀
Read the review by Jorge Manzo and colleagues 👇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Abigail R. Byford from @universityofleeds.bsky.social and colleagues investigated endothelial-to-mesenchymal transition in the #fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational #diabetes🔬🔎
Read the study
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Ignacia González & Rodrigo Maldonado-Agurto examine the role of cellular #senescence in #endothelial dysfunction and #vascular remodelling in arteriovenous fistula maturation 🫀 🔬
Read the review 👇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Ameyalli Gómez-Ilescas and Patricia Pelufo Silveira examine early adversity and the comorbidity between #metabolic disease and #psychopathology ✍️ 🧠
Read the review 👇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Yifeng Dai and colleagues examined the differential effect of #lead and #cadmium on mitochondrial function and NLRP3 inflammasome activation in human #trophoblast 🔬 💉
Read the #Research 👇️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this study, Fernanda Sanhueza-Olivare from @uchile.bsky.social and colleagues performed vascular remodelling in a mouse model of heart failure with preserved ejection fraction💻️ 🫀
Read the #research 👇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Reducing the negative effects of calciprotein particles on endothelial cells in chronic kidney disease: A promising non-pharmaceutical approach'
Stephanie Lapierre-Nguyen & Jigar Gosalia @cuanschutz.bsky.social discuss Feenstra et al. (2026) ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Metabolic heterogeneity of endothelial cells: potential for tissue-targeted therapies in diabetic vascular complications'
Aryan Y. Sarnaik examines the work of McAleese et al. (2026) in this #JournalClub article ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
'Pathophysiological features of pre-clinical HFrEF and HFpEF models'
Alexa N. King from @uofguelph.bsky.social examines the work of Méndez-Fernández et al. (2026) in this #JournalClub article ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
