Interesting synthetic biology effort. But let’s not forget that amino acids are not only used for protein synthesis but also for many other metabolic processes. So while you might get rid of one for protein synthesis I am not sure you can get rid of it completely. But doing it is the way to find out
Carlos Ribeiro
1/ Excited to share our new paper in Science @science.org: “Toward life with a 19-amino acid alphabet through generative artificial intelligence design.” A great collab w/ Sergey's group @sokrypton.org at MIT
@columbiasysbio.bsky.social science.org/doi/10.1126/... 🦠🧬🛠️🖥️💥
Because all known living organisms are made from at least 20 canonical amino acids, the feasibility of life using a more simplified alphabet remains unclear. In this work, we leveraged computational d...