Postdoc fellow @ Stanford & Gladstone Institutes
Core team @scverse-team.bsky.social
Bringing the single-cell genomics in human complex trait genetics
https://emdann.github.io/
Emma Dann
Why do schizophrenia GWAS signals look so flat across the genome?
In our recent preprint, we explored why psychiatric disorders — and, more broadly, brain-related traits involving the central nervous system — appear to have unusual genetic architectures.
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🧬 2026 Internship: Marioni Group @genentech.bsky.social Seeking PhD intern for Deep Learning on large-scale genetic screens (Perturb-seq/Optical).
Focus: ML for single-cell + imaging to decode phenotypes.
📍 SSF (On-site) | 12-wk paid
⚠️ Apply via portal only: 🔗 bit.ly/45P7TQB
#CompBio #AI #Genetics
How well does TWAS estimate a gene’s direction of effect on a trait? We think of this as an important stress-test for the accuracy of TWAS.
In a new pre-print, we find that TWAS gets the sign wrong around 20-30% of the time!
doi.org/10.64898/202...
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Huisheng (Julie) Zhu
Ana Carolina Leote
Nikhil Milind
Transcriptome-wide association studies (TWAS) are widely used to identify genes involved in complex traits and to infer the direction of gene effects on traits. However, despite their popularity, it r...
2026 Summer Intern (Computational Sciences - Cluster of Excellence) The Marioni group in the Computational Sciences (CS) department studies the molecular mechanisms of cell fate decisions in early dev...
