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New research in @natmed.nature.com reveals IgG1 producing #Bcells are key to cancer #immunotherapy success. Data from 2k+ patients show these cells coordinate with T-cells to drive anti-tumor immunity. A shift toward humoral-cellular strategies could transform outcomes. rdcu.be/e90xd
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Nature Medicine - Transcriptomic and clinical data analyses from multiple cohorts of patients with cancer receiving immunotherapy find that PD-1 blockade potentiates tumor-specific IgG1 plasma cell...
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Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade
Infinity Bio Inc