Online now! Online now! Licensed to pore: Gasdermins in action #chembiol
Ketelut-Carneiro, Mathur, and Fitzgerald review the mechanisms and regulation of the different gasdermins (GSDMs) in pyroptosis. They provide a comprehensive overview of the role of GSDMs across infectious and inflammatory diseases and cancer, highlighting key unanswered questions and challenges in targeting GSDMs for therapeutic strategies.