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Fantastic work from @davidovichlab.bsky.social Congrats!
3mo
Steve Turner
1/ 🧵 In our new paper, we show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2. www.cell.com/molecular-ce...
3mo
Some proteins mimic the repressive mark H3K27me3, but the physiological relevance of this phenomenon was unclear. Agius et al. show that the PRC2 subunits JARID2 and PALI1 mimic H3K27me3 to antagonize...
www.cell.com
Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains
Chen Davidovich