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Research Director Group leader at IRIM-CNRS, Co-head of the Autophagy Machinery in Infections team Montpellier University 🇫🇷 www.irim.cnrs.fr Structural biology, antimicrobial resistance, membrane protein, bacterial virulence, Nocardia, Mycobacteria.
Mickaël Blaise
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Special thanks to @agencerecherche.bsky.social for funding the NORESIST project and Jerome Feuillard and Julie Couston @juliecouston.bsky.social from the AMI team for their great work.
6mo
Mickaël Blaise
We are hiring!
4mo
⚡️ Permanent Researcher position opening in Stephane Blanc group at PHIM, INRAE, Montpellier France  “Traffic of viral macromolecules within host plants and role in the biology of multi-component viral systems  🦠 More info 👉 jobs.inrae.fr/concours/con... ❗️Deadline March 4th 2025
Exciting #postdoc opportunity in KL Ung's group! Understanding the molecular mechanisms of cell wall remodeling in pathogens Learn more: shorturl.at/gPuFV Deadline: January 15, 2026 Contact: [email protected] #Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
Glad to share our preprint on the clinically relevant topic of beta-lactam resistance of Nocardia @irim-life.bsky.social. A great collaboration with the lab of Dr.O.Dumitrescu @hospicescivilslyon.bsky.social @ciri-lyon.bsky.social www.biorxiv.org/content/10.1...
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Feb 2, 2025
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We demonstrate a strong correlation between the enzymatic activity of the NCY-1 β-lactamase from a Nocardia cyriacigeorgica clinical isolate and its to β-lactams. We report the crystal structure of NCY-1 bound to avibactam, supporting its broad inhibitory spectrum across Nocardia species.