Good summary of the induced proximity phosphorylation space; still waiting for this to be reduced to practice for therapeutic value in the clinic.....
www.cell.com/cell-chemica...
Ke et al. review emerging proximity-inducing modalities—phosphorylation-targeting
chimera, including PhosTACs, DEPTACs, PhoRCs, and PHICS—that modulate protein phosphorylation
via an “event-driven” me...