People. @ksamuk.bsky.social and others have made this argument before. There’s good software to do this right. Here’s the argument again:
Invariant sites matter! They’re not in your standard vcf and many programs pretend they are anyway.
academic.oup.com/gbe/article/...
Abstract. Many long-standing questions in population genomics can now be addressed through comparative analyses and by leveraging the vast amount of genomi
