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🚀 New from the lab! How do sensory cortices "know" whether they’ll become visual or somatosensory? 🧠 We uncover early modality-identity genes in cortex, some set before thalamic innervation via cell-adhesion codes, others refined by thalamic activity. @glb-lab.bsky.social @neuroalc.bsky.social
6mo
Guille López-Bendito
New preprint on bioRvix! We show how cortical sensory-modality identity is instructed by a combinatorial cell-adhesion and activity codes, using #snRNAseq #spatialtranscriptomics #functional imaging. Congrats to everyone on this work! @guillelbendito.bsky.social @neuroalc.bsky.social
6mo
The emergence of functional sensory modalities requires precise cortical arealization and thalamocortical connectivity. While early morphogen gradients broadly initiate cortical patterning, how sensor...
www.biorxiv.org
Combinatorial Cell-Adhesion and Activity Codes Instruct Cortical Modality Identity
Lopez-Bendito Lab