Our new study reveals how bacterial toxins are physically captured through a sequential, concentration-dependent assembly mechanism before secretion via the T6SS.
Fantastic collaboration with @fillouxlab.bsky.social. Congrats Patricia & Ambre for leading this work.
Paper here: shorturl.at/O31Vn
Structural analysis reveals that the type VI secretion system effector cargo is enclosed within hexameric Hcp3 rings that form sequentially to enable effector loading and delivery by the Pseudomonas aeruginosa H3-type VI secretion system.
