Happy to share the definitive version of our last paper about the role of TET enzymes and DNA demethylation in retinal development @clark-lab-retina.bsky.social journals.plos.org/plosbiology/...
#FluorescenceFriday
The #seahorse #retina shows off its beauty — stunning stratification in the inner nuclear and inner #plexiform layers, with rod #bipolar terminals forming a brilliant band.
#Vertebrate retinas: the same basic plan, yet each species adds its own twist. Its so fascinating.
TET enzymes remove DNA methylation markers, but the role of this process in retinal development is not clear. This study shows that these enzymes are required for photoreceptor cells to initiate the g...
We recently wrote a review about neuroimmune interactions in retinal repair. We dive into the literature regarding immune influences in Muller glia reprogramming, cell transplantation, and axon regeneration. Hopefully its useful, free link: authors.elsevier.com/a/1k-FL4pAsj...
Excited to share our new manuscript from the Yoshimatsu and MacDonald labs. www.biorxiv.org/content/10.6.... We found that my favourite glial cells can regulate local retinoic acid signalling to specialise cone photoreceptors for high acuity visual function.
Ismael Hernández Núñez
ECUSA Midwest celebrará su II Noche Blanca de la Ciencia el 15 de noviembre en el Instituto Cervantes de Chicago.
📅 Escanea los QR para consultar la agenda completa y registrarte en el evento.
📸 Este año lanzamos un concurso de fotografía infantil con 🎁 tres premios para las mejores fotos.
For today’s #FluorescenceFriday, the #rods clearly chose chaos
What you’re looking at are long, beautifully coiled outer segments of rod #photoreceptors… basically the retina showing off its inner spaghetti aesthetic.
Elegant, tangled, and absolutely essential for seeing in low light.
Looking through old photos and found this beauty. Frog rods, labelled with GFP under a XOP promoter (inner segment, orange) and wheat germ agglutinin (outer segments, cyan). I love how you can see the holes where the mitochondria are packed near the top of the inner segment (the ellipsoid zone). 🧪🐸
#FluorescenceFriday
#Seahorse retina stained with #GNB3 (green) + #DAPI (cyan). GNB3 labels cone photoreceptors + ON #bipolarcells, tracing pathways from outer to inner retina. Amazing to see conserved visual #circuits in this non-traditional model
In the spirit 👻 of Freaky Friday 🎃, here is a beautiful yet eery video of zebrafish retina development showing horizontal cells (🔵) finding their way out of the crowded amacrine (🟠) layer to settle beneath the photoreceptors. Happy #Halloween!
🎥: PhD student Rae Wong from the @nordenlab.bsky.social
