clinical trialist, science enthusiast, chronically sub-optimal
Started recreational ended kinda medical
Kevin Gibbs
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Interesting! And a good opportunity to reassess one's priors
In the SNAP trial, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality in patients with methicillin-susceptible Staphylococcus aureus bacteremia and had fewer nephrotoxic effects. Read the full trial results: https://nej.md/4vL0M6m
Induction medication for emergency intubation — does the choice matter? NEJM Editorial Fellow Katerina Lin, MD, explains a randomized trial to determine the effects of ketamine vs. etomidate for induction of anesthesia during emergency tracheal intubation. Full RSI trial results: nej.md/44EOlxB
Among critically ill adults with acute respiratory failure, neither carbocisteine nor hypertonic saline reduced the duration of mechanical ventilation, and each strategy was associated with harm. Full phase 3 MARCH trial results: https://nej.md/3PUyHdA
#CCR26 | @criticalcarereviews.com
Video
New #DAS2025 guidelines for management of unanticipated difficult adult #trachealintubation with an emphasis on maximising likelihood of success at the #firstattempt
https://www.bjanaesthesia.org/article/S0007-0912(25)00693-2/fulltext
NEJM.org
NEJM.org
CCR26 returns to Belfast in June with 12 superb trials
🔴 Cardiac arrest
🔴 Sepsis
🔴 Acidaemia
🔴 Paeds nutrition
🔴 Burns
🔴 Respiratory failure
🔴 Sedation
🔴 Transfusion
🔴 Post ICU care
📍 Titanic Belfast
📅 June 10–12, 2026
Registration is open!
criticalcarereviews.com/meetings/ccr26
#CCR26 Conservative oxygen therapy, vs usual oxygen therapy, did not significantly affect the % of patients with cardiac arrest receiving invasive mechanical ventilation in the ICU who survived with a favourable functional outcome @dogicuma.bsky.social Manuscript now available online @nejm.org
Critical Care Reviews Meeting 2026, Titanic Belfast, June 10th to 12th. Featuring 12 major critical care trial results
