3/
In this study, we introduce SCIBED, a computational framework that uses realistic simulations and tailored evaluation metrics to evaluate and compare these methods, helping researchers to make informed choices.
Marta Moreno Gonzalez
2/
❓What is it about?
Single-cell data is inherently noisy and incomplete. Although numerous algorithms exist to fill in missing data in single-cell gene expression, their performance on single-cell histone data has not been systematically explored yet.
📄 The paper: academic.oup.com/nargab/artic...
💻 Software: github.com/KindLab/SCIBED
1/
🧬 Very excited to share our work on dissecting imputation strategies for single-cell histone modification data! academic.oup.com/nargab/artic...
A huge thank you to @robinhweide.bsky.social, @jopkind.bsky.social and Jeroen de Ridder for their collaboration in this project!