Professor at Cornell BME. Studying the neurobiology of psychiatric #drugs including #ketamine and #psychedelics.
https://alexkwanlab.org
Alex Kwan
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A few years back we started a collaboration to try to work out the mechanisms engaged by DBS for depression. Published today we found that it changes functional networks (expected) but also remodels specific white matter tracts (unexpected). Read more here: www.nature.com/articles/s41...
In a nonhuman primate model, Fujimoto et al. show that deep brain stimulation promotes white matter remodeling and reorganizes brain-wide functional networks, detailing a mechanism through which this ...
This was a great read to learn about Mu-ming’s “pathfinding in neurobiology”.
We crossed paths briefly in Berkeley and then I was glad to have visited ION in early 2010s. His effort to lift neuroscience in China has been incredible.
We built this with the goal of making the data accessible and useful for the community. We’re currently in beta testing and would love feedback.
If you’re interested in trying it out, feel free to message me here or email me, and I’ll send you the link!
So I built a small tool that merges Allen CCFv3 with the traditional bregma-relative coordinate system (calibrated with Paxinos & Franklin's Atlas). Click any coronal or sagittal section, and get coordinates instantly.
bohanzhao.com/Atlas
Hope it saves someone a headache 🐭
Excited to share an early look at psilo-seq, a web portal for exploring our lab’s single-nucleus RNA-seq data in mice following psychedelic treatment.
If you are at #SOBP2026 @sobp-org.bsky.social -
Friday poster F159 - travel awardee 👏 Neil Savalia will talk about psychedelics, 5-HT2A/1A receptors, and imaging dendrites 🔬
Saturday poster S170 - travel awardee 👏 Pasha Davoudian will show work on psilocybin and GABAergic interneurons 🧠
Rudebeck Lab
Initial preprint: www.biorxiv.org/content/10.1..., to be updated soon.
The current dataset includes >300,000 nuclei from mouse medial frontal cortex, spanning multiple timepoints (1-72 hours) after psilocybin or ketamine administration alongside controls. Cell types were annotated based on Allen Institute MapMyCell tool .
Now accepting proposals for ISSR 2027! Please share widely!
