Nonenzymatic self-replication of nucleic acids is driven by helicity type A! The unique structure of RNA is predisposed to nonenzymatic copying, and DNA can be copied on an RNA template. Is this why nature chose RNA?
Great work by Barbara, from my group!
pubs.rsc.org/en/content/a...
We performed classical molecular dynamics simulations for DNA self-replication on an RNA template with phosphoroimidazole activation. We demonstrate that the RNA template imposes A-type helicity on th...
