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Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.
Morning #DukeSCIRIP #SingleCell research talks were great! Thanks to presenters from @dukemedschool.bsky.social: Eric Benner of #Pediatrics, Amy Petty of #Dermatology & Boxun Li of #CAGT - info on everyone's work available below. And thanks to @yaruidiao.bsky.social for hosting this session! 🧬🧠🧪🧫🥼
3mo
May 12, 2025
Yarui Diao
The Gregory Lab @ DukeU
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR - @yaruidiao.bsky.social @dukehealth.bsky.social go.nature.com/4rZqimf
3mo
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR - Nature Biotechnology
Trimodal single-cell analysis reveals gene-regulatory architecture in complex tissues.
go.nature.com
Nature Biotechnology