Nice article about Josh and Matt and their work together on this paper.
Uchicago undergrads are very special!
chemistry.uchicago.edu/news/new-uch...
How an innovative UChicago laboratory built a fast-moving platform to target "undruggable" cancer proteins and train the next generation of scientific leaders
This work is now out at @pnas.org
In drug discovery it’s often said selectivity is key - and here is a solution!
Our PANCS platforms continue to expand!
www.pnas.org/doi/10.1073/...
Bryan Dickinson
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
Check out our newest work! This is a story on how to get selectivity in binders - both isoform and site selectivity. Read the paper or enjoy this brief Skytorial of what we did!
www.biorxiv.org/content/10.1...
1/n
Proteins that bind to a target protein of interest, termed "binders," are essential components of biological research reagents and therapeutics. Target proteins present multiple binding surfaces with ...
