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Excited to share our new paper on predicting gene expression in yeast! We introduce "Shorkie," a supervised ML model that builds off a self-supervised foundation to interpret regulatory DNA. Preprint: www.biorxiv.org/content/10.1...
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Predicting gene expression from DNA sequence remains challenging due to complex regulatory codes. We introduce a masked DNA language model pretrained on 165 fungal genomes closely related to budding y...
www.biorxiv.org
Predicting dynamic expression patterns in budding yeast with a fungal DNA language model
David Kelley