Pleased to share that FEMA-Long is now published in PLOS Genetics! FEMA-Long, an efficient mixed-effects modeling method, includes modeling unstructured covariance, spline and spline interactions, and performing longitudinal GWAS to discover time-dependent genetic effects
doi.org/10.1371/jour...
Author summary Most large-scale datasets have complexities such as repeated measures, related individuals, or other dependencies across samples, preventing the use of standard regression approaches fo...