Urosepsis by multidrug-resistant Nakaseomyces glabratus with non-functional Erg3 and Erg11—do collateral sensitivity and a unique mode of action make nitroxoline a viable UTI antifungal? | mBio journals.asm.org/doi/10.1128/...
Evolutionary theory states that fitness determines survival. In a drug-treatment environment,
resistance increases fitness, but it often comes at a cost, such as slower growth
or reduced stress tolera...