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Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8 www.biorxiv.org/content/10.6...
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Noxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined....
www.biorxiv.org
Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling
Marcin Szczot