Epithelial cell death, cell extrusion, self-organisation, mechanotransduction and many other things
Levayer Lab
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๐ Congrats to ElisaโฏGomezโPerdigueroโฏ&โฏBriceโฏBathellier, winners of the 2026โฏValleryโRadotโฏPrize ! ๐
Their work advances our understanding of immune cell originsโฏ&โฏhow the brain processes sound โ showcasing Pasteurian excellence. ๐
@labnf.bsky.social
๐ข We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social!
Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues โ all in the heart of Paris.
Institut Pasteur | 130 years of biomedical research
Lara Krรผger
Our latest manuscript on (Harry Potter and) the effect of elevated temperature on embryonic development in flies. Even a small increase in temperature causes developmental defects, indicating problems in the face of global warming! www.nature.com/articles/s41...
Happy to share our new review on biophysical principles of cell competition and elimination:
www.cell.com/trends/cell-...
With @bladoux.bsky.social and @rmmege.bsky.social, we discuss mechanical fitness, how loser cells are removed through various strategies and how forces can effect their fate
Kale et al. show that nuclear divisions are defective at elevated temperature, leading to gastrulation defects and embryo lethality. Their work finds that F-actin โ microtubule interactions during mit...
๐ฅ ๐ New preprint! ๐๐ฅณ
How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order ๐ช
๐งต๐ (1/17)
Video
This exciting paper is now out in PNAS: www.pnas.org/doi/10.1073/...
Really happy to share my PhD story about the regulation of developmental speed in the Drosophila eye ๐ชฐ๐๐, which is now published @embojournal.org:
link.springer.com/article/10.1...
Grateful to everyone who make this possible, particularly F. Schweisguth @pasteur.fr @devstempasteur.bsky.social
The @sfb1348.bsky.social Meeting โMechanochemical Signals at Cellular Interfacesโ is just around the corner! We are excited to welcome an outstanding lineup of international speakers to #Mรผnster for three days of inspiring scientific exchange and discussion. @uni-muenster.de
Andreas Schoenit
Girish Kale
Please repost !! SANTA CRUZ DEVELOPMENTAL BIOLOGY CONFERENCE 2026. Deadline to register your abstracts for the meeting is Monday June 1. Please get those abstracts in !
scdb2026.sites.ucsc.edu
Cell behaviors in multicellular organisms are coordinated via both diffusible molecules
and by signals based on direct cell–cell contacts. The mode...
Thrilled to share the first story from my postdoc! ๐ A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below โฌ๏ธ
Video
Giulia Paci
Glad to see this out in its final form!
www.nature.com/articles/s41...
What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks @natcellbio.nature.com & reviewers ๐
Autorino et al. report a feedback loop between Nodal signalling and tissue phase transitions in zebrafish embryos. Nodal alters adhesion, triggering tissue rigidification and reduced porosity, which l...
Here our latest work on how morphogens trigger tissue phase transitions to tune their own length-scales and time-scales - An exciting collaboration with @zhvas.bsky.social @dianakhorom.bsky.social Bernat Corominas-Murtra and heroic experiments by the incredible @cami-autorino.bsky.social @embl.org
๐ Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org โจ
โA closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamicsโ ๐ ๐ ๐ถ
๐ www.biorxiv.org/content/10.1...
#devbio #biophysics
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