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Online now: Closing the alkene–alkyne gap
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A recent study by Meng et al. reports the direct desaturation of alkenes to alkynes, addressing a century-old synthetic challenge. Utilizing a recyclable selenanthrene reagent, this methodology operates under mild conditions with high selectivity. Broad functional group tolerance enables late-stage transformation of complex molecules, providing sustainable routes to versatile alkynes.
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Closing the alkene–alkyne gap
Trends in Chemistry