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by @jimpick.com
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So how do mRNAs get localised at specific areas of the cell if there are no unifying sequence or structural patterns? Work from the labs of @simonbullock11.bsky.social @carter-lab.bsky.social @natsmb.nature.com provides insightful answers to this longstanding question. www.nature.com/articles/s41...
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Singh et al. combine cryo-electron microscopy and functional studies to reveal how a single protein complex selects diverse mRNAs for subcellular localization using a combination of shape, positional ...
www.nature.com
Structural basis for recognition of diverse localizing mRNAs by Egl–BicD - Nature Structural & Molecular Biology