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Focusing the power of genomics to create a healthier world. Leader in pangenomics, conservation genomics, cancer genomics, pathogen genomics, and nanopore sequencing. Home of the UCSC Genome Browser, @ucscxena, UShER, Dockstore, and other high-power tools.
UC Santa Cruz Genomics Institute









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New vg v1.74.0 "Petrie" update includes: šŸ”¹Single-command way to run the haplotype sampling mapping workflow with vg giraffe šŸ”¹ Minimap2-inspired alignment scoring approach for giraffe šŸ”¹Ability to write v.1 GBZ files for compatibility with pangenome-aware DeepVariant github.com/vgteam/vg/re...
Gene editing requires embryos, but hydra almost never reproduce sexually. So how do you study their legendary regenerative genes? The Macias-MuƱoz CnidoLab found a way to get a 5Ɨ increase in egg yield. šŸ”¬
Congratulations to our graduating Research Mentoring Internship (RMI) scholars - we are so proud of you!
šŸ§¬šŸ‡ÆšŸ‡µ @ucsantacruz.bsky.social Genomics Institute researchers have collaborated to sequence near-complete Japanese genetic data, unlocking complex, medically relevant DNA regions. This work is part of the effort to dismantle reference bias for globally equitable medicine. www.nature.com/articles/s41...
@benedictpaten.bsky.social @adamnovak.graphs.vg @thinks.lol @jltsiren.bsky.social @xian-chang.bsky.social @jmonlong.bsky.social
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Like its mythical counterpart, real-life hydra are nearly immortal, and can regrow any body part. And scientists just got much better at studying them. New work from the Aide Macias-MuƱoz lab is a quiet but meaningful leap for evolutionary genetics. Learn more: integrativeandcompar...
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In my lab's latest, we experimentally test the decades-old idea that plants switch from bee to hummingbird pollinators in tropical mountains because bee activity declines in cool cloud forest conditions nph.onlinelibrary.wiley.com/doi/10.1111/...
UC Santa Cruz Genomics Institute
UC Santa Cruz Genomics Institute
UC Santa Cruz Genomics Institute
UC Santa Cruz Genomics Institute
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UC Santa Cruz Genomics Institute
UC Santa Cruz Genomics Institute
The new statewide Stream Health Index powered by environmental DNA (eDNA) will allow us to work faster and smarter to assess how watersheds are responding to stressors like wildfires, climate change, and agricultural runoff. This method will lower evaluation costs to just a few hundred dollars.
In the 1980s, disease wiped out about 99% of black abalone. A new study from @ucsantacruz.bsky.social sequences whole genomes from shells, a feat no one had accomplished before, to reconstruct what abalone populations looked like pre-collapse: news.ucsc.edu/2026/05/anci... šŸ“·Michael Ready