Microbiomes are remarkably stable across most of adult life, then deteriorate in old age. What is actually holding them together? Our proposal: immune surveillance. A framework inspired by immune oncology, applied to the microbial community at every mucosal surface.
journals.plos.org
Host-associated microbiomes are stable across most of the lifespan, but what drives late-life deterioration remains unclear. This Unsolved Mystery proposes interventions that restore immune surveillan...
