Thrilled to see this out today in PLOS Biology. With postdocs Siqi Liu and Flávio Costa, we ask why the gut microbiome loses its balance with age. It's an Unsolved Mystery piece: a framework, not a finalized account, with predictions we lay out for the field to test. 🧵
Dario Riccardo Valenzano
Host-associated microbiomes are stable across most of the lifespan, but what drives late-life deterioration remains unclear. @dvalenzano.bsky.social &co propose interventions that restore #immune surveillance capacity alongside ecologically informed #microbiome management.
🧪 #aging
Host-associated microbiomes are stable across most of the lifespan, but what drives late-life deterioration remains unclear. This Unsolved Mystery proposes interventions that restore immune…
