cryoEM 🧪🧊🦠 is the workhorse of structural bio. But it struggles with smaller proteins. New studies in @science.org & @biorxivpreprint.bsky.social report 'laser phase plate' designs to overcome that limitation. @eisensteinium.bsky.social explains @nature.com www.nature.com/articles/d41...
www.nature.com
After years of effort, two research teams have developed ‘laser phase plate’ systems that could help cryo-electron-microscopy users to generate high-quality structures for a broad range of proteins.
