EPI-Clone is a transgene-free lineage tracing method that uses single-cell DNA methylation analysis to track hematopoietic stem cell clones over time #NBThighlight www.nature.com/articles/s41...
The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing th...