ICYMI: New online! Pleiotropic effects of cis-regulatory mutations
Nature Reviews Genetics, Published online: 28 May 2026; doi:10.1038/s41576-026-00981-zIn this Comment, Patricia Wittkopp revisits assumptions that cis-regulatory mutations are weakly pleiotropic, ultimately calling for more data to assess the extent to which they are less pleiotropic and deleterious than trans-regulatory mutations.
