New online! RNA design across eras: from covariance models to modern generative AI
Nature Reviews Genetics, Published online: 08 May 2026; doi:10.1038/s41576-026-00967-xIn this Journal Club, Annalisa Marsico describes a 1994 paper by Eddy and Durbin that formalized RNA sequence analysis with covariance models, which are powerful tools more recently applied to generative machine learning models for RNA design.
