Delighted to share our latest collaborative research paper with my long term collaborators Nigel Greig and W. Douglas Figg showing Thalidomide-like monoterpenoid analogues, unlike classic IMiDs, lack cereblon binding and they have anti-angiogenesis actions.
www.sciencedirect.com/science/arti...
Immunomodulatory imide drugs (IMiDs) designed on the backbone of thalidomide are highly effective in the treatment of multiple myeloma (MM). However, …